Vitamin D-Binding Protein (Gc-Globulin) in Acute Liver Failure in Children
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منابع مشابه
Localization and quantitation of the vitamin D binding protein (Gc-globulin) in human neutrophils.
Plasma-derived vitamin D binding protein (DBP) is an important physiologic regulator of the neutrophil chemotactic response to activated complement. A cell-associated form of DBP has been observed in numerous cell types. We now report that mature, circulating human neutrophils also contain cell-associated DBP. Immunofluorescence studies of normal untreated neutrophils showed the presence of DBP...
متن کامل"Rocket" immunoelectrophoresis assay of vitamin D-binding protein (Gc globulin) in human serum.
suchung mit 51Cr-EDTA im abfallenden Plasmaspiegel. Atompraxis 13,357-360 (1967). 5. Stacy, B. D., and Thorburn, G. D., Chromiuin-51-ethylenediaminetetraacetate for the estimation of gbomerular filtration rate. Science 152, 1076-1077 (1966). 6. Watkin, D. M., Barrows, C. H., Jr., and Chow, B. F., Renal clearance of intravenously administered vitamin B12.Proc. Soc. Exp. Biol. Med. 107, 219-221 (...
متن کاملMean Serum Concentration of Vitamin D-binding Protein (Gc Globulin) Is Related to the Gc Phenotype in Women | Clinical Chemistry
Gc is the major carrier protein of vitamin D and its metabolites in the circulation and is important for preservation of the vitamin (4)(5). Gc also transports components such as fatty acids and endotoxin (6)(7), and it is an important player in the actin scavenging system (8)(9). Gc binds actin released from cells upon injury, and the Gc-actin complexes are rapidly cleared from the circulation...
متن کاملMean serum concentration of vitamin D-binding protein (Gc globulin) is related to the Gc phenotype in women.
cause mild overtreatment, i.e., a reduction in dietary Phe allowances in excess of metabolic tolerance. This is not critical with Phe concentrations at or above the upper limit of normal. Still, neurological outcome has also been demonstrated to be adversely affected by Phe deficiency (14 ). In view of an overestimation by up to 60 mmol/L in the low concentration range and a target range of 40–...
متن کاملPossible Association between Dysfunction of Vitamin D Binding Protein (GC Globulin) and Migraine Attacks
To identify the genetic causality of migraine and acute, severe melalgia, we performed a linkage analysis and exome sequencing in a family with four affected individuals. We identified a variant (R21L) in exon 2 of the GC globulin gene, which is involved in the transportation of vitamin D metabolites and acts as a chemotaxic factor; this variant was co-segregated within the family. To investiga...
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ژورنال
عنوان ژورنال: Diagnostics
سال: 2020
ISSN: 2075-4418
DOI: 10.3390/diagnostics10050278